Question of the Week #119, 120, 121

119) A 60-year-old woman presents to the Emergency Room with massive hemetemesis. The onset is acute. She denies any alcohol use or  any antecedent nausea, vomiting or retching. On physical examination, the patient is found to be hypotensive with a blood pressure of 80/40. The patient is started on Intravenos fluids and proton pump inhibitors. Prothrombin time and liver function tests are with in normal limits. Hemoglobin is low at 7gm/dl and the patient is now being transfused with 2 units of packed red cells. An immediate Endoscopy is scheduled which revealed bleeding gastric varices but no esophageal varices. Local vasocontrictor therapy and band ligation could not restrain thebleeding. Ultrasound and CT scan of abdomen revealed enlarged spleen, an engorged splenic artery and an intraluminal filling defect in the Splenic Vein as shown in the picture below

The most common etiology of the condition mentioned above :
A) Polycythemia Vera
B) Inherited Thrombophilias
C) Liver Cirrhosis
D) Chronic Pancreatitis
E) Carcinoma Pancreas
120) The pathophysiology behind the development of Varices in this patient :
A) Systemic Portal Hypertension
B) Superior Mesenteric Vein Thrombosis
C) Liver Cirrhosis
D) Sinistral Portal Hypertension
E) Angiodysplasia
121) The most effective treatment for the condition described above:
A) Transjugular Intrahepatic Portosystemic Shunt
B) Thrombolysis
C) Anticoagulation with heparin
D) Splenectomy

 

12 Responses

  1. ddddd
    dddddd
    ccccccc

  2. a
    a
    d

  3. CBC

  4. D
    The condition is isolated splenic vein thrombosis, which is most commonly due to chonic pancreatitis.
    D
    Splenic vein thrombosis results in sinistral or left sided portal hypertension.
    D

  5. 3 Ds

  6. d
    d
    d

  7. D
    D
    D

  8. d
    d
    d

  9. E
    D
    D

  10. d,d,d

  11. CT abdomen may show mass at tail of pancreas,splenomegaly and splenic vein thrombosis

  12. sure
    d
    d
    d

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