Question of the Week # 155

155)  A 55 year old man presents to the clinic for progressive right hip pain. He has a history of hearing impairment. He reports pain in the right hip when walking more than 1 block and also, has difficulty putting shoes on his right foot. On examination, the range of motion is significantly limited in the right hip. An X-ray of the right hip reveals significant loss of cartilage, subchondral sclerosis and sub-chondral cysts. X-ray also reveals pagetoid changes in the right iliac wing and right femoral neck. Serum alkaline phosphatase level is 432 IU/L (n = 20 to 140 IU/L). The most appropriate initial step in managing this patient is:

A)           Bisphosphanates

B)            Acetaminophen

C)            Bisphosphanates and Acetaminoiphen

D)           Calcitonin Intranasally

E)           Oral prednisone

Question of the Week # 152

152) A 34 year old woman with history of recently diagnosed Rheumatoid Arthritis presents to your office for follow up. She reports much improvement in her symptoms after starting Ibuprofen for pain. She was also started on Hydroxychloroquine 3 weeks ago. Which of the following is most appropriate in monitoring her therapy?

A)     Liver function tests every month

B)      Complete Blood Count every 3 months

C)      Serum Creatinine every week

D)     Ophthalmologic evaluation every year

E)      Hydroxychloroquine serum levels every month